Hotkeys stop working, left click becomes ping, Enter switches me between fullscreen and windowed.

Seemingly without pattern, all of my hotkeys stop working entirely (and alt is not stuck) and my left clicks become pings. When I hit enter, the game will switch to windowed, and when I hit enter again, it switches back to fullscreen. Hitting escape does nothing, and this continues until it decides it will let me play the game again. This happens when I'm walking to lane, when I come back from dying, when I am in the middle of a fight, and at any point in the game. It's happened in the first 2 minutes of the match, it's happened 35 minutes into the match. Thank you for your time.
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